ID: 4069
Year: 2025
Products: Elemental Scientific Lasers
Authors: Beyer, K;Carter, A;Dussubieux, L;
Application: ~
Previous studies of Iron Age (500 BC–AD 500) Southeast Asian glass ornaments have almost exclusively examined glass beads comprising the majority of glass ornament assemblages at Iron Age Southeast Asian sites. When mentioned, other ornament types (e.g., rings, bangles, and earrings) are typically fragmented or in otherwise poor condition. This study is one of the first to report on the elemental compositions of complete rare glass ornaments—specifically, a collection of seven complete glass earrings, five complete glass bangles, and a single spiral ornament. These objects were donated to the University of Oregon
for repatriation to Cambodia and are believed to originate from the site of Phum Snay, Cambodia. Using primarily LA-ICP-MS compositional data of six collection objects, we contextualize this collection within the corpus of glass ornaments that circulated in Iron Age Southeast Asia as well as contemporaneous glass trade networks and associated spheres of influence. Results ...
ID: 4062
Year: 2025
Products: NWR 193 nm
Authors: Rocca, M;
Application: isotope;
The timing of deformation in the central Southern Alps (cSA) of Italy has been debated due to challenges in determining both relative and absolute chronologies in this area of the European Alps. Past studies provided relative time constraints via crosscutting relationships among faults, folds, and intrusive bodies, supported by stratigraphy, while absolute ages have been determined for fault activity in the crystalline basement and for magmatic bodies cutting across primary structures. These efforts have clarified the tectonic and sedimentary evolution of the cSA during the Alpine orogeny. However, many studies relied on qualitative approaches or broad time estimates, leaving uncertainties about the precise timing of events, particularly in the Mesozoic sedimentary cover. The absence of absolute time constraints in the frontal cSA relates to the prevalence of brittle deformation in the Mesozoic carbonate sequence. Though crustal faults and fractures have been studied, absolute dating o...
ID: 4061
Year: 2025
Products: Product Unavailable
Authors: Ștreangă, IM;
Application: Dissolved;Speciation;Species;seawater;
Iodine holds significant importance across various disciplines, including medicine, industrial processes, organic synthesis, paleoclimatology, atmospheric chemistry and modern climate science. The ocean, as a major surficial iodine reservoir and the primary source of this element to the atmosphere, plays a central role in global iodine cycling. Despite significant progress, key aspects of iodine cycling in the marine environment remain poorly understood. This thesis leverages recent advances in high-precision techniques, including liquid chromatography and mass spectrometry, to enhance our understanding of marine iodine biogeochemistry. Detailed analyses of the major inorganic iodine species in seawater, iodide and iodate, were conducted in the oligotrophic waters of the North Pacific and the oxygen minimum zones of the Eastern Tropical Pacific. The observed distributions reflect the impact of both in situ and ex situ processes on dissolved iodine concentrations, offering valuable insi...
ID: 4060
Year: 2025
Products: micromill system (ESI)
Authors: Hsieh, CY;Liu, TY;Tseng, YC;Shirai, K;
Application: ~
Adjustments in the metabolism of marine fish are associated with the complexity of resource availability, prey-predator relationships, and biotic and abiotic interactions in the natural environment. To investigate the relationship between metabolism and body mass, this study used a conventional method to estimate the oxygen consumption rate (reflecting the resting metabolic rate) in black porgy, Acanthopagrus schlegelii, over a year of rearing. In addition, we developed a novel metabolic proxy using the δ13C values of vertebral structural carbonates to monitor lifelong metabolic changes. The oxygen consumption measurements followed a decreasing mass-dependent trend and yielded a mass-specific allometric exponent scaling (−0.24). By integrating the oxygen consumption with the advanced δ13C metabolic proxy, we established a decay model in an increasing form to describe the relationship of the two measurements, and it could be further used in wild fishes and broaden the metabolic stud...
ID: 4059
Year: 2025
Products: Apex™ dissolving nebulizer
Authors: Siklosi, Z;Osztas, A;Bajnoczi, B;Villa, IM;Nisi, S;
Application: isotope;
In the second half of the Late Neolithic (4700 − 4500 cal BCE), the first malachite and copper artefacts appeared in large quantities in the territory of present-day Hungary. They are known only as grave goods such as beads, rings and bracelets. Copper artefacts are concentrated in South-eastern Transdanubia, and archaeological literature has argued that this copper wealth may have been due to the exploitation of local malachite resources in the Mecsek Mountains. In our study, we compared lead isotope and chemical composition measurements of Mecsek malachite sources, Late Neolithic malachite and copper artefacts, and other potential ore sources to investigate the provenance of the raw material of these artefacts. The results of our analysis clearly exclude the exploitation of local, Mecsek sources. The malachite and copper artefacts found in the same grave may have come from the same source in the majority of the cases. This suggests that a set of ornaments was made using either ...
ID: 4058
Year: 2025
Products: NWRfemto femtosecond laser ablation system
Authors: Zhang, J;Yang, Y;Wang, Q;Zhang, H;Zhu, F;
Application: Laser;geochemistry;
We present new mineralogical and chemical data on quartz and stibnite from the Woxi Au-Sb-W deposit in western Hunan. The aim is to elucidate the substitution mechanisms of trace elements and to estimate the ore-forming temperatures within the Woxi deposit. Furthermore, we explore the potential of using trace element compositions in quartz to differentiate between various types of mineral deposits. Based on field investigation and petrographic observation, the mineralization process of the Woxi deposit can be divided into three distinct stages: an early quartz-scheelite stage, a main quartz-sulfide-native gold stage, and a late quartz-carbonate stage. LA-ICP-MS analysis of quartz from different mineralization stages reveals distinct substitution mechanisms for trace elements. In the early-stage quartz, the primary substitution mechanism is (Al³⁺, As³⁺) + (Li⁺, Na⁺) → Si⁴⁺. In the main stage, the substitution mechanism is 2(Sb³⁺, As³⁺) + (Ba²⁺) → 2Si⁴⁺. Fo...
ID: 4056
Year: 2025
Products: PFA MicroFlow nebulizer
Authors: Pereira, C;Edwards, J;Khasanova, A;Carlson, A;Brisson, V;Schaefer, E;Rio, T;Tringe, S;Vogel, J;Marais, D;Juenger, T;Mueller, U;
Application: Tissue;Total;agricultural;
Microbiome breeding by host-mediated selection is a technique to artificially select for microbiomes conferring benefits to plants. Here, we describe leaf ionomics, microbial community composition, and network analyses of a microbiome-breeding experiment to generate microbiomes conferring salt tolerance to Brachypodium distachyon, a model for cereal crops. Plants receiving microbiomes selected to confer tolerance to either sodium- or aluminium-stress produced 69-198% higher total seed weight than plants receiving control microbiomes. Sodium-selected microbiomes reduced leaf-sodium concentration by 50%, whereas aluminium-selected microbiomes had no effect on leaf-tissue nutrient concentration, suggesting different mechanisms underlying microbiome-mediated salt tolerance. By testing these selected microbiomes in a cross-fostering experiment, we show that artificially-selected microbiomes attain (a) ecological robustness contributing to transplantability (inheritance) of microbiome-encode...
ID: 4055
Year: 2025
Products: ESL NWR 193 Excimer laser with a TwoVol3 ablation cell
Authors: Larson, KP;Cottle, JM;Shrestha, S;
Application: Laser;
New in situ apatite U-Pb and mica Rb-Sr and 40Ar/39Ar geochronology outline a break in geochronology within the Mount Everest massif at an elevation of c. 8000 m. Above the break, most chronometers record dates from the Eocene epoch, whereas below, most dates are from the Middle Miocene epoch. Raman spectroscopy of carbonaceous material and Ti-in-biotite-based thermometry results outline a break in temperatures at the same elevation. From the summit downwards, temperatures increase to a maximum of c. 500°C at c. 8500 m before decreasing to c. 400°C at c. 7900 m. The coinciding breaks in the independent datasets are interpreted to reflect movement along a previously unrecognized structure, here termed the Adrishya thrust that was active c. 18 Ma. The Adrishya thrust may reflect re-equilibration of the evolving orogenic wedge, perhaps further influenced by cooling and strain localization structurally away from the exhuming orogenic core....
ID: 4054
Year: 2025
Products: ESI
Authors: Bamba Bukengu Muhaya, ;Benjamin Busomoke Badarhi, ;Emery Mutombo Kalonda, ;
Application: Environmental;Total;drinking water;
Groundwater, surface water and tap water contamination by PTEs (Potentially Toxic Elements) was assessed in Kipushi town and Lupoto locality of Kipushi administrative territory in the Upper-Katanga province, Democratic Republic of Congo. A total of fifty four water samples including thirty two samples from drilled water wells, ten samples from spade-sunk water wells, six samples from supplied tap water, four samples from a mine effluent and two samples from a river were collected from both localities in November and December 2017 and in January, February and March 2018. Then the samples were analyzed for their PTE contents by ICP-SF-MS (Inductively Coupled Plasma-Sector Field Mass Spectrometry). Twenty PTEs including aluminum, arsenic, barium, bismuth, cadmium, cesium, chromium, cobalt, copper, iron, lead, manganese, molybdenum, nickel, strontium, thallium, tungsten, uranium, vanadium and zinc were detected at various concentrations in each one of the samples. Many samples had concentr...
ID: 4053
Year: 2025
Products: Product Unavailable
Authors: Chao, H;Sun, F;Wang, T;Yang, Y;Chai, Y;Yan, J;Bakht, S;Li, B;Zhang, Y;Tao, Y;Chen, X;Liu, C;Zhu, X;Wang, Y;Wang, Z;Li, H;Song, R;Dou, D;
Application: geochemistry;
Permian magmatic rocks are extensively distributed in the East Kunlun Orogenic Belt (EKOB), yet controversies persist regarding the petrogenesis of granitoid and the tectonic evolution of the Buqingshan-A’nyemaqing Ocean (BAO), a Paleo-Tethys oceanic branch. This study addresses these debates through petrological analyses, whole-rock geochemistry, and zircon U-Pb-Lu-Hf isotopic investigations of newly identified granitoids in the EKOB. The monzogranite (MG) and quartz porphyry (QP) yield weighted mean ages of 254.7 ± 1.1 Ma and 254.3 ± 1.1 Ma, respectively. Geochemically, the MG shows metaluminous to weakly peraluminous low-K calc-alkaline I-type granites, characterized by high SiO2, low K2O, MgO, FeOT contents, and marked enrichment in light rare earth elements (LREEs), but depletion in Eu, Ba, Sr, P and Ti anomalies. In contrast, the QP exhibits peraluminous high-K calc-alkaline I-type affinities, displaying high SiO2 but low Na2O and P2O5 contents. It...
ID: 4052
Year: 2025
Products: TwoVol2
Authors: Gibson, S;Jackson, C;Crosby, J;Day, J;
Application: ~
The deep cratonic ‘roots’ of Earth's major continents extend over 160 km and have remained stable for more than 2.5 billion years. This longevity is primarily due to the presence of low-density, refractory peridotites (harzburgites) that formed by extensive mantle melting in the Archean. However, mantle harzburgites from some global cratons (e.g., Kaapvaal, Siberia, Slave, Rae and Tanzania) often show unusual enrichments in orthopyroxene and silica, alongside titanium depletion, which cannot be explained by simple melting processes. The proposed origins of the orthopyroxene-rich harzburgites are highly controversial and include high-pressure melting residues, komatiite interactions, or subduction-related silicic melts and fluids. The uncertainty primarily arises because of the inherent difficulties involved in reconstructing the tectonic settings responsible for the stabilisation of early Earth. To investigate further, we analysed volatile (H₂O, F, Cl) contents in Kaapvaal craton...
ID: 4051
Year: 2025
Products: Elemental Scientific Lasers
Authors: Yang, Z;Li, H;Lu, Y;Hou, Z;
Application: Laser;
Abstract The Tethyan orogenic belt underwent prolonged tectonic evolution and hosts numerous world-class porphyry copper deposits. Notably, most porphyry deposits are associated with Cenozoic continental collision, while fewer are formed during Mesozoic subduction. Here we integrate detrital zircon oxybarometry with geochemical data, stratigraphy, sea-level and temperature fluctuations, and major geological events. Our results reveal a stark redox transition-from anoxic during Mesozoic subduction to oxidized during Cenozoic collision. We propose that subduction of organic-rich, reduced sediments in the Mesozoic suppressed the oxidation state of arc magmas, locking chalcophile elements in the lower crust and inhibiting the formation of subduction-related porphyry Cu deposits. In contrast, the subduction of more oxidized sediments during the Cenozoic elevated oxygen fugacity, releasing stored metals and promoting extensive formation of porphyry Cu deposits during continental collision. T...
ID: 4047
Year: 2025
Products: ESI NWR193UC, Excimer Ablation cell ESI NWR TwoVol2
Authors: Bonilla, A;Piraquive, A;Cramer, T;Franco, J;Cogné, N;
Application: Laser;
The northwesternmost portion of the Amazonian Craton outcrops in Eastern Colombia consists predominantly of Proterozoic tectonometamorphic provinces whose rocks range in age from 1.85 to 0.6 Ga. The assembly of the NW Amazonian Craton entails a complex and extensive geological history comprising most of the Proterozoic era, which is mostly poorly understood because of the lack of well-defined temporal and stratigraphic constraints. In this work, we present new zircon and apatite U-Pb data from two samples from the medium-to-high-grade rocks of the Guaviare Complex. From zircon U-Pb ages, the protolith age of the Guaviare Complex has been constrained at ca 1.3 Ga. However, in the present database as well as in our newly produced data, the conspicuous presence of a significant population of discordant ages was revisited showing zircon U-Pb ages that might indicate a reheating event between 1.0 to 0.6 Ga. Apatite U-Pb data from the same samples reinforces this interpretation by revealing ...
ID: 4046
Year: 2025
Products: autosampler (SC2-DX, 2DXCi,
Authors: Meister, M;Sharma, S;He, X;Chepaitis, P;Waddey, T;Wilson, M;Premnath, V;Jeevarajan, J;Black, M;Wright, C;
Application: Cells;Biological;Species;
The occurrence of thermal runaway (TR) events continues to rise as the need for lithium-ion batteries (LIB) for energy storage increases. However, the inhalation risks associated with LIB TR events remain widely unknown. The objective of this study was to evaluate the impact of LIB TR particulate emission exposures on primary small airway epithelial cells (SAEC). TR was triggered by subjecting lithium-ion cells to thermal abuse at different states of charge (SOC). The test articles had two different battery cathode chemistry compositions, namely, nickel manganese cobalt (NMC) or lithium iron phosphate (LFP). Aerosol monitoring and sampling instrumentation were employed followed by physicochemical particle characterization and inhalation dosimetry modeling. SAEC were treated with TR particulate emission extracts for 24 h and 7 days at doses representing a cumulative 1- and 5-year inhalation exposure. Following treatment, cellular viability, reactive oxygen species (ROS) production, and ...
ID: 4045
Year: 2025
Products: APEX Q nebulizer
Authors: Hao, Y;Strähl, J;Khare, P;Cui, T;Schneider-Beltran, K;Qi, L;Wang, D;Top, J;Surdu, M;Bhattu, D;Bhowmik, H;Vats, P;Rai, P;Kumar, V;Ganguly, D;Szidat, S;Uzu, G;Jaffrezo, J;Elazzouzi, R;Rastogi, N;Slowik, J;Haddad, I;Tripathi, S;Prévôt, A;Dällenbach, K;
Application: agricultural;
Ambient particulate matter significantly impacts air quality, climate, and human health. In the Indo-Gangetic Plain (IGP), home to nearly one-seventh of global population, severe air pollution is prevalent with high PM2.5 levels dominated by organic aerosols (OA). However, the sources and formation of OA pollution remain poorly constrained. For the first time, we characterize OA sources in two cities, i.e., Delhi and Kanpur in the IGP, over an entire year by combining near-molecular characterizations using an extractive electrospray ionization time-of-flight mass spectrometer (EESI-TOF) combined with advanced statistical approaches. We found three key local biomass burning sources—affected by various fuels such as wood, straw, and cow dung—that had a more pronounced impact on Kanpur (66%) compared to Delhi (35%), particularly during colder months. Additionally, we identified transported agricultural fire emissions from Northwest India, which significantly contributed to OA during t...
ID: 4044
Year: 2025
Products: micromilling system (MicroMill
Authors: Cheng, L;Lee, Y;Lai, C;Lo, Y;Shiao, J;Weng, J;He, J;Huang, H;
Application: Environmental;isotope;
In this study, we reconstructed the early-life migration patterns of narrow-barred Spanish mackerel (Scomberomorus commerson) in the northwestern Pacific by using time-series otolith δ18O analysis. Specimens collected from Taiwanese waters between 2013 and 2023 were analysed, and over 75% showed no significant seasonal variation in δ18O values. However, specimens from 2016 to 2017 and from 2020 to 2021 had lower δ¹⁸O values in autumn than in summer. Two distinct migration patterns were identified. The first pattern involved movement along the coasts of China, western Taiwan, and the Taiwan Strait from late spring to summer, followed by southward migration to southwestern Taiwan, southeastern China, the southern Taiwan Strait, and the northern South China Sea in winter, with a return northward by early spring. The second pattern was similar but included a northward expansion into the East China Sea by mid-to-late summer, followed by a southward return in late autumn and winter. Bo...
ID: 4043
Year: 2025
Products: imageGEO193 fitted with a TwoVol3 ablation chamber,
Authors: Chrást, P;Komendová, R;Barták, M;Zvěřina, O;
Application: Biological;Laser;
This study employed laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) to investigate the spatial distribution of potentially toxic elements in Usnea antarctica from James Ross Island, Antarctica. A triple quadrupole ICP-MS system coupled with a next-generation laser ablation system enabled 15 μm spatial resolution, facilitating the acquisition of detailed quantitative bioimages. Bioimages captured Cr, Cu, Co, Ni, Mn, Fe, Zn, Pb, and U distributions across lichen pseudotissues, revealing allocation patterns between the cortical, photobiont, and medullary regions. These elemental distribution trends support previous Antarctic biomonitoring studies, demonstrating consistency in long-range metal transport, deposition patterns, and metabolic pathways. High-speed triple-quadrupole acquisition and refined laser probe spatial resolution provided an improved framework for elemental bioimaging in complex biological matrices. The results indicated preferential accumulation ...
ID: 4042
Year: 2025
Products: seaFAST-pico
Authors: Li, J;Kong, KP;Streanga, IM;
Application: Dissolved;isotope;
Siderophores, small ferric iron (Fe)-binding metabolites, are biomarkers of microbial Fe-stress. Here we report the results from two experiments profiling the distribution of 57Fe-siderophore uptake performed in late summer of 2021 and 2022 near Station ALOHA, the long-term ecological study site of the Hawaii Ocean Time-series program located in the North Pacific Subtropical Gyre. The experiments were designed to investigate how changes in microbial Fe-stress in upper mesopelagic waters (200-400 m) respond to temporal changes in dissolved Fe. Nearly complete uptake (92-99%) of added 57Fe-siderophores was observed in the upper mesopelagic; however, the depths at which siderophore uptake was most active differed between experiments. In 2021 nearly complete uptake of added siderophores occurred at depths between 200 m and 350 m, while in 2022 the region of complete uptake was restricted to waters between 300 m and 350 m. The differences in siderophore uptake between the 200 m and 250 m ex...
ID: 4041
Year: 2025
Products: seaFAST
Authors: Kong, KP;Yang, SC;Barone, B;Hamilton, DS;
Application: Biological;Dissolved;Total;seawater;isotope;
Highly productive summer phytoplankton blooms in the central North Pacific Subtropical Gyre (NPSG) are a near annual occurrence that lead to the export of significant amounts of surface particulate carbon being exported to depth. The cause for the formation of these blooms remains unresolved, but the availability iron (Fe) may be a potentially important factor controlling productivity in the central NPSG. From July to October 2022, a large persistent phytoplankton bloom formed around 23.3{degree sign}N, 154.6{degree sign}W that was observable through satellite imagery. We measured elevated Fe concentrations within the bloom that might have stimulated nitrogen (N2) fixation. We estimate that waters that hosted the diazotroph-fueled bloom received up to 20 percent more soluble and total Fe through aerosol deposition than in nearby waters that passed through locations outside the bloom. Even though this moderate increase does not represent incontrovertible evidence that the bloom was stim...
ID: 4040
Year: 2025
Products: Product Unavailable
Authors: Sluis, M;Lippi, D;Sanchez, P;Miller, N;Stephens, S;Ferreira, B;Rooker, J;
Application: Species;Laser;
Different applications of inductively coupled plasma mass spectrometry (ICP-MS) have the potential to influence results of otolith geochemical assays. Laser ablation and solution-based ICP-MS were compared on paired otoliths from three species of juvenile fish representative of estuarine (red drum [ Sciaenops ocellatus ]), coastal/reef (gray parrotfish [ Sparisoma axillare ]), and pelagic (blackfin tuna [ Thunnus atlanticus ]) ecosystems. Additionally, two laser ablation techniques (continuous line transects and series of spots) were performed to determine whether these two commonly used approaches yielded comparable results. No significant differences existed between line transects and spots for any of the three species investigated, with high correlations occurring for all otolith element:Ca (E:Ca) values retained for statistical testing (Mg:Ca, Mn:Ca, Sr:Ca, Ba:Ca), suggesting that both laser ablation techniques produced equivalent otolith E:Ca values. In contrast, pronounced differ...
ID: 4039
Year: 2025
Products: Product Unavailable
Authors: YUE, H;ZHAI, Y;CAO, Y;LI, H;WU, M;YU, H;QIU, K;
Application: Total;geochemistry;
To determine the geological age, petrogenesis, and tectonic setting of Mesozoic volcanic rocks in the Ningyuancun Formation in Xunke area, Lesser Hinggan Range, the zircon U-Pb geochronology, petrographic observations, and geochemical analyses of major and trace elements were conducted in this study. Zircon U-Pb dating showed that the volcanic rocks of the Ningyuancun Formation were formed in the Early Cretaceous (112.97±0.90 Ma). Major element analyses revealed that the content of SiO₂ weighted from 74.14% to 76.54%, indicating the volcanic rocks to be high-silica and felsic. The content of Al₂O₃ varies from 12.48% to 13.65%. A total alkali content of the volcanic rocks range between 8.46% and 9.56%, with Na₂O/K₂O ratios from 0.69 to 0.89. This indicated that the volcanic rocks belonged to a highly differentiated calc-alkaline series. Additionally, A/CNK values range from 0.950 to 1.015, and A/NK values vary between 0.999 and 1.127, suggesting a peraluminous characteristic....
ID: 4038
Year: 2025
Products: seaFAST
Authors: Schmidt, C;Zimmermann, T;Koziorowska‐Makuch, K;Pröfrock, D;Thomas, H;
Application: Biological;Dissolved;seawater;
Abstract. The west Greenland shelf is a dynamic marine environment influenced by various physicochemical and biological processes. This study provides an overview of the main factors affecting the distribution of macronutrients, carbonate system parameters, and dissolved trace elements during late summer. Key drivers include major ocean currents, melting sea ice, and terrestrial freshwater runoff, each uniquely contributing to the cycling and spatial distribution of chemical constituents. Major ocean currents, such as the southward-moving Baffin Island Current (BIC) and the northward-moving West Greenland Current (WGC), shape the chemical composition of shelf waters by introducing water masses with distinct chemical signatures. Melting sea ice is an important source of freshwater and dissolved constituents for the marine environment. The east-to-west direction of sea ice retreat creates nutrient gradients, with low nutrient levels in highly productive shelf waters and high nutrient lev...
ID: 4037
Year: 2025
Products: apex Q nebulizer
Authors: Paglione, M;Hao, Y;Decesari, S;Russo, M;Mansour, K;Mazzola, M;Fellin, D;Mazzanti, A;Tagliavini, E;Manousakas, M;Diapouli, E;Barbaro, E;Feltracco, M;Daellenbach, K;Rinaldi, M;
Application: Species;nuclear;
Abstract. Understanding the chemical composition and sources of organic aerosol (OA) in the Arctic is critical given its importance for particle climate-relevant properties. This study presents a year-long analysis (May 2019-June 2020) of PM1 filter samples collected in Ny-Ålesund, Svalbard. A multi-instrumental approach is employed to characterize the comprehensive chemical composition of PM1, with a specific focus on its water-soluble organic fraction (WSOA) depicted combining proton nuclear magnetic resonance spectroscopy (H-NMR) and high-resolution time-of-flight aerosol mass spectrometry (HR-TOF-AMS), which provide complementary insights on nature and structure of the organic aerosol classes characterizing the bulk OA mixture. Positive Matrix Factorization (PMF) source apportionment identifies consistent OA sources from the H-NMR and AMS datasets, showing a pronounced seasonality in OA contributions. Winter-spring aerosol is dominated by long-range transport of Eurasian anthropog...
ID: 4036
Year: 2025
Products: Product Unavailable
Authors: Cao, Q;Chen, X;
Application: Environmental;Food;Drug;Laser;agricultural;
Microfluidic chips can condense an entire analytical detection laboratory into a chip of just a few square centimeters, achieving miniaturization, integration, automation, and high-sensitivity. The main microfluidic detection technologies include electrochemical detection technology, capacitively coupled contactless conductivity detection technology, and photoelectric detection technology, which are now widely used in environmental monitoring, food safety testing, drug testing, disease diagnosis, and agricultural detection. In this chapter, we summarize the typical analytical methods integrated onto microfluidic platforms. Applications of these microfluidic analytical methods on environment, food safety, biomedicine, and other fields also have been discussed. At last, the challenges and future directions about microfluidics-based analysis development have been remarked....
ID: 4035
Year: 2025
Products: Elemental Scientific Lasers
Authors: Ahn, SH;Halgren, K;Grzesiak, G;MacRenaris, KW;Sue, A;Xie, H;Demireva, E;O'Halloran, TV;Petroff, MG;
Application: Cells;Laser;
Autoimmune regulator (AIRE), a transcription factor expressed by medullary thymic epithelial cells, is required for shaping the self-antigen tolerant T cell receptor repertoire. Humans with mutations in AIRE suffer from Autoimmune Polyglandular Syndrome Type 1 (APS-1). Among many symptoms, men with APS-1 commonly experience testicular insufficiency and infertility, but the mechanisms causing infertility are unknown. Using an Aire -deficient mouse model, we demonstrate that male subfertility is caused by sterile epididymitis characterized by immune cell infiltration and extensive fibrosis. In addition, we reveal that the presence of autoreactive immune cells and inflammation in epididymides of Aire- deficient mice are required for iron (Fe) deposition in the interstitium, which is brought on by macrophages. We further demonstrate that male subfertility is associated with a decrease in metals zinc (Zn), copper (Cu), and selenium (Se) which serve as cofactors in several antioxidant enzyme...
ID: 4034
Year: 2025
Products: SC-4 DX FAST autosample
Authors: Saito, MA;McIlvin, MR;
Application: Biological;Environmental;
Pseudomonas aeruginosa is a major contributor to human infections and is widely distributed in the environment. Its ability for growth under aerobic and anaerobic conditions provides adaptability to environmental changes and to confront immune responses. We applied high-throughput native 2-dimensional metalloproteomics to P. aeruginosa to examine how use of iron within the metallome responds to oxic and anoxic conditions. Metalloproteomic analyses revealed four major iron peaks, each comprised of metalloproteins with synergistic functions, including: 1) respiratory and metabolic enzymes, 2) oxidative stress response enzymes, 3) DNA synthesis and nitrogen assimilation enzymes, and 4) denitrification enzymes and related copper enzymes. Three ferritins co-eluted with the first and third iron peaks, localizing iron storage with these functions. Several metalloenzymes were more abundant at low oxygen, including alkylhydroperoxide reductase C that deactivates organic radicals produced by den...
ID: 4033
Year: 2025
Products: 2DX PrepFAST M5 autosampler
Authors: Gokhale, A;Mendez-Vazquez, H;Sampson, MM;Moctezuma, FGR;Harbuzariu, A;Sing, A;Zlatic, SA;Roberts, AM;Prajapati, M;Roberts, BR;Bartnikas, TB;Wood, LB;Sloan, SA;Faundez, V;Werner, E;
Application: Biological;Environmental;
Manganese (Mn) is an essential trace element required for various biological functions, but excessive Mn levels are neurotoxic and lead to significant health concerns. The mechanisms underlying Mn-induced neurotoxicity remain poorly understood. Neuropathological studies of affected brain regions reveal astrogliosis, and neuronal loss, along with evidence of neuroinflammation. Here, we present a novel Mn-dependent mechanism linking mitochondrial dysfunction to neuroinflammation. We found that Mn disrupts mitochondrial transcriptome processing, resulting in the accumulation of complementary RNAs that form double-stranded RNA (dsRNA). This dsRNA is released to the cytoplasm, where it activates cytosolic sensor pathways, triggering type I interferon responses and inflammatory cytokine production. This mechanism is present in 100-day human cerebral organoids, where Mn-induced inflammatory responses are observed predominantly in mature astrocytes. Similar effects were observed in vivo in a m...
ID: 4032
Year: 2025
Products: ESI PrepFAST autosampler
Authors: Näkki, P;Ahvo, A;Turja, R;Sainio, E;Koistinen, A;Hartikainen, S;Peräniemi, S;Stankevičiūtė, M;Pažusienė, J;Lehtonen, K;Setälä, O;Lehtiniemi, M;
Application: Environmental;Species;
Abstract Car tyres are considered to release a substantial amount of particles to the environment. Due to the high emission volumes and the chemical risks associated with tyre rubber, there is an urgent need to quantify their ecotoxicological effects. The effects of exposure to particles derived from end-of-life tyres were investigated on the Baltic clam ( Macoma balthica ), which is one of the key invertebrate species living in the soft-bottom sediments of the northern Baltic Sea. Tyre rubber particles (10-188 µm) were added to the aquaria in an environmentally relevant concentration (1.08 g per kg dry sediment), and the clams had either direct or indirect contact to the particles for 5 and 29 days. The effects of exposure were studied by applying a battery of biomarkers and cell ultrastructure examination of clam tissues, and the concentrations of selected polycyclic aromatic hydrocarbons and trace metals originating from tyre rubber were quantified from the exposure water and clam ...
ID: 4031
Year: 2025
Products: ESI SC-2 DX4 autosampler
Authors: A Sizova, E;A Miroshnikov, S;V Notova, S;V Skalny, A;V Yausheva, E;M Kamirova, A;A Tinkov, A;
Application: Serum;
The objective of the present study was to evaluate serum and fecal trace element and mineral levels in Red Steppe dairy cows with different daily milk yields during the transition from feedlot to pasture. Serum and fecal trace element and mineral levels were assessed using the inductively coupled plasma mass spectrometry. The obtained data demonstrate that serum Ca, Mg, K, and Na levels increased significantly in the pasture period, and this increase is more profound in cows with higher milk yield. In turn, circulating levels of B, Co, Cr, Fe, I, and Se significantly decreased in the pasture period. Despite the lack of group differences in the feedlot period, serum B, Cr, and Fe levels in the pasture period were higher in cows with higher milk yield. In turn, circulating Co and I concentrations were higher in the cows with lower milk yield. Finally, the levels of toxic trace elements in the pasture period were found to be higher in cows with lower milk productivity. Discriminant analys...
ID: 4030
Year: 2025
Products: Elemental Scientific PFA MicroFlow
Authors: Nunez, EA;Fabregat, RG;Ruiz, IM;
Application: ~
This article presents the rationale behind the material culture from Rochelongue underwater site assemblage. This site was located in the 1960s at Cap d’Agde (Languedoc-Rousillon, France) and dated to the last quarter of the seventh-beginning of the sixth century BC. The study is based on the characterisation of the metal finds linked to the so-called “Launacian” phenomenon. The results are applied within the context of mobility, connectivity and cultural interaction, showing metal as the central defining element of these archaeological contexts. The provenance and cultural affiliations of the pieces, determined from chemical and provenance analyses, help, in turn, to determine interactions between the Iberian Peninsula and the rest of Europe. In this context, the South of France is a nexus for direct contact sustained over a certain period, probably economic, although never free from other socio-political considerations. Thus, the article opens debate on the underwater site of R...
