microFAST Isotope2 – Automated Precision Injection for Isotope Ratio Analysis
The Isotope2 is a second generation sample injection system designed specifically for the determination of isotope ratios by multicollector ICPMS. Design features take into consideration the challenges associated with the determination high precision (<10 ppm = 0.001%) isotope ratios in less than 1 mL of sample volume.
Key Features & Benefits
- Syringe loading & injection – Precise and accurate volume uptake (software) & stable injection of sample
- FluoroWand – Prevents evaporation
- ULPAclean 10 – Ultraclean environment for sample integrity
- Chemically resistant FNXS autosampler – no metal exposure to sample, low contamination and corrosion
FluoroWand In Action
Isotope2 Features Diagram
FluoroWand
Automatically Removes & Replaces Covers
FluoroWand permits racked sample vials to remain individually covered, except at the moment when the sample is being taken up for analysis. The FluoroWand reduces the risk of environmental contamination and minimizes solution evaporation rates thereby maintaining concentration matching of samples and standards throughout an analytical run.
Maintain Sample/Standard Integrity by Minimizing Contamination and Evaporation
- Automatically remove and replace covers from PFA sample containers
- Compatible with wide range of Sample and Standard vials (<1 ml to 100 ml)
- High Capacity for extended analytical sessions (>120 sample capacity)
Benefits
- Reduce sample evaporation by > an order of magnitude
- Prevent environmental sample contamination
- Minimize acid vapors
Fluoronetic Autosampler
ESI Fluoronetic autosamplers are the most robust, chemically resistant autosamplers on the market, featuring ESI's 100% fluoropolymer magnetically coupled linear drive.
- Highest chemical resistance of any autosampler
- Magnetically coupled fluoropolymer linear drive eliminates exposed metal components
- Autocorrecting position autosampler - keeps analysis running, even after obstruction
- Vertical lift doors provide easy access to samples on all four sides
- Air shower and ULPA filter options to ensure clean environment for samples
- Longitudinal PTFE exhaust manifold in sample deck to remove sample fumes
- Clean autosampler for laboratories without a cleanroom
Syringe Injection Profile Stability
The Isotope2 system, when combined with the Apex Omega, demonstrates exceptional injection profile stability across a range of flow rates (50, 100, and 150 μL/min). The system consistently achieves excellent injection reproducibility with an RSD of less than 1.0% at all each flow rate. This high level of precision is maintained across multiple injection profiles—fifteen in total, with five at each flow rate—resulting in internal precision of less than 1.5% for all profiles.
*All data collected in combination with Apex Omega.
Magnetic SnapValves and Loops
The Isotope2 is equipped with innovative Magnetic SnapValves to streamline installation and maintenance. Simply snap on and off with your hands, eliminating the need for tools. All valve ports are marked with clear labels to improve user experience and minimize confusion when attaching lines.
- Innovative Technology - patented magnetic attachment
- Easy Installation - Simply snap on and off, no tools needed to remove from drive
- Simple Maintenance - cleaning procedure takes seconds
- LED Display - Responsive to status of FAST method
Apex Omega
The Apex Omega desolvating system is the highest performing ICPMS sample introduction system available. An innovative multistage Peltier-cooled desolvation system combined in series with a helical EPTFE fluoropolymer membrane desolvator simultaneously maximizes ICPMS sensitivity and reduces oxides.
- Increase sensitivity by 6x to more than 10x, depending upon sample flow rate
- Significantly reduce oxides and solvent removal (0.01% CeO+/Ce+)
- Two stage desolvation (Peltier-cooled and EPTFE membrane) imparts matrix tolerance higher than any membrane desolvator on the market
- Features complete software control of:
- Ar sweep gas mass flow controller
- N2 addition gas mass flow controller
- Heated spray chamber temperature
- Peltier-cooled condenser temperature
- Heated membrane temperature
- Micro peristaltic drain pump
ULPA Air Filter
The ULPAclean 10 (Ultra-Low Particle Arrester) filter creates a clean, positive pressure environment for samples and standards and prevents airborne contamination. It removes 99.9995% of 0.1 µm or larger particles. The mounting plate is compatible with all DX autosampler Clean3V enclosures.
| Part # | Description |
|---|---|
| ULPA10 | ULPAclean-10 filter for ESI Clean3V Enclosures |
| Power | Air Volume |
|---|---|
| 24VDC | 1.0 (m3/min) or 0.5 (m3/min) |
IsotopeBench
The IsotopeBench is an all-in-one solution for your laboratory. IsotopeBench is built from metal-free materials and comfortably holds Isotope2, Apex Omega, with additional storage cabinets and drawers. Engineered with a compact footprint to optimize space utilization, this system enhances laboratory efficiency while offering ample storage capacity. It's innovative waste and exhaust management system is vital to improving the safety of labs.
- Designed for Isotope2 & Apex Omega systems
- Metal-free and corrosion-free
- Improve lab safety with waste & exhaust management
- Welded polypropylene
Syringe Injection Long Term Stability
Li isotope ratios are measured using the Isotope2 system. Syringe injecting 100 μL of sample at 20 μL/min provides nearly 5 minutes of steady state signal for isotope ratio analysis. External reproducibility is improved for the smallest absolute sample amounts (6 ng) using low volume solution aliquots.
Benefits
- < 2% RSD over 16hr run
- Three hundred (5 min) injections
- Nd is used to illustrate long term stability
- Syringe injection combined with Apex desolvation is the most stable platform for isotope ratio analysis
Long Term Reproducibility (16 hrs)
Five 1mL injection profiles at 100 μL/min
Improved Wash Out
Each flow path is washed with 3mL of rinse solution before loading next sample. This fast wash provides superior washout relative to self-aspiration which is limited to the sample analysis flowrate (typically 100 μL/min).
Isotope2 Wash Out vs Self-Aspiration
10 Hour Wash Out Study
* All data collected in combination with Apex Omega.
FluoroWand for Minimizing Contamination and Evaporation
The FluoroWand reduces the risk of environmental contamination and minimizes solution evaporation rates thereby maintaining concentration matching of samples and standards throughout an analytical run.
Percent Change Concentration After 10 Hours
- Reduces sample (1mL) evaporation by >10x
- Reduces standard (10mL) evaporation by >10x
- <2% change in absolute concentration
- <0.2% change in concentration between samples and standards
microFAST Isotope2
(shown with Apex Omega & IsotopeBench)
microFAST Isotope2